EPA and DHA serve many important roles, including the health of our nervous system. the most unsaturated membrane the phospholipids of the cerebral cortex and retina, and is an important contributor to membrane fluidity.1 DHA deficiency affects neurotransmission, membrane activities, gene expression, inflammation, immunity and synaptic plasticity; and is associated with normal ageing, Alzheimer’s disease, hyperactivity, schizophrenia, and peroxisomal disorders.2 EPA has important roles with neural signalling, synapse formati shown to help with depressive symptoms. Although commonly referred to as essential as they can be formed in the body via the c This conversion process, however, can be very slow, and may be inadequate in certain circumstances: elevated dietary saturated fats, cholesterol, trans a glucose-rich diet, alcohol, adrenaline, glucocorticoids, age, diabetes and deficiencies of pyridoxine, zinc and magnesium inhibit the desaturase enzymes required for the endogenous formation of EPA and DHA.4 This makes DHA and EPA under certain conditions the requirements for these fatty acids may exceed the individual's capacity to synthesise them. The most significant dietary source of EPA and DHA is marine fish: in western societies the rate of fish consumption is often low. Supplementati DHA is therefore ideal to optimise the body’s levels of these fatty acids.